Link: https://en.wikipedia.org/wiki/Fumaric_acid
Description: WebFumarate is an intermediate in the citric acid cycle used by cells to produce energy in the form of adenosine triphosphate (ATP) from food. It is formed by the oxidation of succinate by the enzyme succinate dehydrogenase. Fumarate is then converted by the enzyme fumarase to malate .
DA: 79 PA: 81 MOZ Rank: 76
Link: https://www.webmd.com/drugs/2/drug-4689-8274/quetiapine-oral/quetiapine-oral/details
Description: WebQuetiapine FUMARATE - Uses, Side Effects, and More. Common Brand (S): Seroquel. Generic Name (S): quetiapine. Uses. This medication is used to treat certain mental/ mood disorders (such as...
DA: 1 PA: 39 MOZ Rank: 59
Link: https://pubchem.ncbi.nlm.nih.gov/compound/fumarate
Description: WebDescription. Fumarate (2-) is a C4-dicarboxylate that is the E-isomer of but-2-enedioate (2-) It has a role as a metabolite, a human metabolite and a Saccharomyces cerevisiae metabolite. It is a butenedioate and a C4-dicarboxylate. It is a …
DA: 29 PA: 81 MOZ Rank: 21
Link: https://www.merriam-webster.com/dictionary/fumarate
Description: WebFeb 26, 2024 · fu· ma· rate ˈfyü-mə-ˌrāt. : a salt or ester of fumaric acid. Examples of fumarate in a Sentence. Recent Examples on the Web Ferrous fumarate: This is an iron salt that may cause GI upset.
DA: 32 PA: 17 MOZ Rank: 82
Link: https://pubmed.ncbi.nlm.nih.gov/21440919/
Description: WebAlthough much is now known about fumarate metabolism, our knowledge of some aspects of its biological function remain far from comprehensive. In this short review we begin with an introductory overview of the role of fumarate in both plant and non-plant systems.
DA: 89 PA: 42 MOZ Rank: 29
Link: https://www.sciencedirect.com/science/article/pii/S003194221100118X
Description: WebJun 1, 2011 · Biological function of fumarate metabolism remains far from comprehensive. Here the relative importance of fumarate is discussed. The involvement of fumarate in pH regulation and stomatal movement is shown. Engineering the fumarate metabolism may provide opportunities to improve plant growth.
DA: 25 PA: 97 MOZ Rank: 38
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803114/
Description: WebDec 12, 2021 · Fumarate is a terminal electron acceptor in the mammalian electron transport chain - PMC. Journal List. HHS Author Manuscripts. PMC8803114. As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of …
DA: 69 PA: 56 MOZ Rank: 28
Link: https://www.science.org/doi/10.1126/science.abi7495
Description: WebDec 2, 2021 · Fumarate is a terminal electron acceptor in the mammalian electron transport chain. Jessica B. Spinelli, Paul C. Rosen , Hans-Georg Sprenger, Anna M. Puszynska, [...], and David M. Sabatini +9 authors Authors Info & Affiliations. Science. 2 Dec 2021. Vol 374, Issue 6572. pp. 1227 - 1237. DOI: 10.1126/science.abi7495. Reversing the chain.
DA: 99 PA: 86 MOZ Rank: 53
Link: https://www.nature.com/articles/s41589-022-01052-0
Description: WebJun 16, 2022 · Mechanistically, fumarate is a covalent inhibitor of tyrosine kinase LYN, a key component of the BCR signaling pathway. Fumarate can directly succinate LYN at C381 and abrogate LYN activity,...
DA: 9 PA: 37 MOZ Rank: 2
Link: https://www.cell.com/trends/cell-biology/fulltext/S0962-8924(23)00209-X
Description: WebNov 6, 2023 · Fumarate hydratase (FH) and fumarate are now known to regulate cytokine production. Recent findings suggest FH loss leads to mitochondrial nucleic acid release, leading to type I interferon production. Abstract. Tricarboxylic acid (TCA) cycle metabolites have been implicated in modulating signalling pathways in immune cells.
DA: 73 PA: 32 MOZ Rank: 52