Link: https://emcrit.org/ibcc/acetaminophen/
Description: WEBOct 8, 2021 · Rumack-Matthew Nomogram . This predicts the likelihood of hepatic failure based on acetaminophen level following a one-time ingestion. Disagreement exists regarding the ideal cutoff used in the nomogram, as shown above. To err on the side of caution, it may be safest to use the United Kingdom treatment line.
DA: 57 PA: 33 MOZ Rank: 44
Link: https://en.wikipedia.org/wiki/Rumack–Matthew_nomogram
Description: WEBThe Rumack–Matthew nomogram, also known as the acetaminophen nomogram, is an acetaminophen toxicity nomogram. It plots serum concentration of acetaminophen against the time since ingestion, in order to predict possible liver toxicity and allow a clinician to decide whether to proceed with N-Acetylcysteine (NAC) treatment.
DA: 70 PA: 46 MOZ Rank: 88
Link: https://www.ncbi.nlm.nih.gov/books/NBK441917/
Description: WEBJun 9, 2023 · If serum levels fall into the toxic range based on the Rumack-Matthew Nomogram, then treatment should be initiated. A level greater than 150 mcg/mL at 4 hours from ingestion is considered toxic. Serum levels must be drawn between 4 to 24 hours from the time of ingestion to use the nomogram properly.
DA: 35 PA: 55 MOZ Rank: 90
Link: https://emedicine.medscape.com/article/820200-workup
Description: WEBFeb 2, 2017 · The Rumack-Matthew nomogram uses the serum acetaminophen concentration, in relation to the time after ingestion, to assess potential hepatotoxicity after a single, acute ingestion of...
DA: 1 PA: 76 MOZ Rank: 35
Link: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808062
Description: WEBAug 8, 2023 · Revised Rumack-Matthew Nomogram for the Acute Ingestion of Acetaminophen. The original Rumack-Matthew nomogram line, derived from patient data, begins at 200 μg/mL at 4 hours after ingestion. The treatment line (safety line) beginning at 150 μg/mL at 4 hours was derived as 25% lower than the original nomogram line.
DA: 67 PA: 67 MOZ Rank: 12
Link: https://www.tylenolprofessional.com/sites/tylenol_hcp_us/files/acetaminphen_overdose_treatment_info.pdf
Description: WEBbelow the treatment line on the treatment nomogram (Chart 1). Interpretation of acetaminophen assays The Rumack-Matthew nomogram is used to interpret the acetaminophen level (Chart 1). If the initial acetaminophen level plots above the treatment line (starting at 150 mcg/mL at 4 hours), then acetylcysteine treatment is recommended.
DA: 42 PA: 14 MOZ Rank: 79
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913076/
Description: WEBJun 6, 2016 · The initial purpose of the Rumack-Matthew nomogram was for acute ingestions of APAP and its use has not been validated for chronic ingestions, extended-release preparations or co-ingestions of APAP with other substances that may be hepatically cleared.
DA: 2 PA: 8 MOZ Rank: 48
Link: https://www.merckmanuals.com/professional/multimedia/figure/rumack-matthew-nomogram-for-single-acute-acetaminophen-ingestions
Description: WEBRumack-Matthew nomogram for single acute acetaminophen ingestions. Semilogarithmic plot of plasma acetaminophen levels vs time. Cautions for use of this nomogram: The time coordinates refer to time after ingestion. Serum levels drawn before 4 hours may not represent peak levels.
DA: 33 PA: 12 MOZ Rank: 87
Link: https://www.uptodate.com/contents/acetaminophen-paracetamol-poisoning-in-adults-pathophysiology-presentation-and-evaluation
Description: WEBDec 5, 2023 · Using the Revised Rumack-Matthew nomogram - Ingestion of extended-release formulation or anticholinergic/opioid co-ingestion; Evaluation after repeated supratherapeutic ingestion - Assessing risk for hepatotoxicity after RSTI - Need for treatment with acetylcysteine; Evaluation following delayed presentation with …
DA: 9 PA: 51 MOZ Rank: 52
Link: https://www.uptodate.com/contents/acetaminophen-paracetamol-poisoning-management-in-adults-and-children
Description: WEBDec 5, 2023 · Evaluation and diagnosis of acetaminophen poisoning, use of the Revised Rumack-Matthew nomogram, and determination of risk of liver injury (see "Acetaminophen (paracetamol) poisoning in adults: Pathophysiology, presentation, and evaluation" and "Clinical manifestations and diagnosis of acetaminophen (paracetamol) …
DA: 55 PA: 25 MOZ Rank: 79