Link: https://www.nature.com/articles/ncomms3368
Description: WEBSep 9, 2013 · RecG and UvsW catalyse robust DNA rewinding critical for stalled DNA replication fork rescue | Nature Communications. Article. Open access. Published: 09 September 2013. RecG and UvsW catalyse...
DA: 43 PA: 45 MOZ Rank: 32
Link: https://pubmed.ncbi.nlm.nih.gov/27038615/
Description: WEBThe RecG protein of Escherichia coli is a double-stranded DNA translocase that unwinds a variety of branched substrates in vitro. Although initially associated with homologous recombination and DNA repair, studies of cells lacking RecG over the past 25 years have led to the suggestion that the prote ….
DA: 52 PA: 44 MOZ Rank: 31
Link: https://www.sciencedirect.com/science/article/pii/S1568786409003425
Description: WEBMar 2, 2010 · Without RecG, PriA triggers a cascade of events that interfere with the duplication and segregation of chromosomes. Here we review the studies that led us to this idea and to conclude that RecG may be both a specialist activity and a general guardian of the genome. 1. Introduction.
DA: 46 PA: 86 MOZ Rank: 17
Link: https://www.nature.com/articles/srep09625
Description: WEBApr 29, 2015 · The RecG DNA helicase a key player in stalled replication fork rescue. The single-stranded DNA binding protein (SSB) participates in this process, but its role in the interaction of RecG with...
DA: 54 PA: 87 MOZ Rank: 67
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534331/
Description: WEBAug 2, 2023 · In contrast, RecG unwinds 4 base pairs per ATP hydrolyzed . Assays to measure nucleoside triphosphate hydrolysis and product release (ADP and/or P i) have been used extensively to determine helicase activity, ascertain energy efficiency and determine the role of NTP utilization in the biochemical mechanism of DNA helicases.
DA: 64 PA: 62 MOZ Rank: 68
Link: https://academic.oup.com/nar/article/27/15/3049/2549167
Description: WEBAug 1, 1999 · The RecG helicase of Escherichia coli is necessary for efficient recombination and repair of DNA in vivo and has been shown to catalyse the unwinding of DNA junctions in vitro. Despite these findings, the precise role of RecG remains elusive.
DA: 5 PA: 61 MOZ Rank: 37
Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038270
Description: WEBJun 6, 2012 · The superfamily 2 bacterial helicase, RecG, is a monomeric enzyme with a role in DNA repair by reversing stalled replication forks. The helicase must act specifically and rapidly to prevent replication fork collapse. We have shown that RecG binds tightly and rapidly to four-strand oligonucleotide junctions, which mimic a stalled replication fork.
DA: 12 PA: 21 MOZ Rank: 39
Link: https://pubmed.ncbi.nlm.nih.gov/20093100/
Description: WEBMar 2, 2010 · The RecG protein of Escherichia coli is a double-stranded DNA translocase that unwinds a variety of branched DNAs in vitro, including Holliday junctions, replication forks, D-loops and R-loops. Coupled with the reported pleiotropy of recG mutations, this broad range of potential targets has made it hard to pin down what the protein does in …
DA: 45 PA: 86 MOZ Rank: 34
Link: https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1005799
Description: WEBFeb 12, 2016 · Here, we investigate the genomic consequences of the absence of RecG during DNA repair following a site-specific double-strand break introduced in only one of two homologous E. coli chromosomes. Our observations suggest that RecG can re-model branched intermediates of recombination to direct the correct binding of PriA.
DA: 5 PA: 17 MOZ Rank: 12
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894433/
Description: WEBApr 29, 2015 · We discovered that RecG is capable of binding to the fork in two different modes and SSB is involved in this conformation switch enhancing RecG loading efficiency and remodeling the helicase. As a result, remodeled RecG separates from the fork, but remains bound to the parental DNA duplex arm.
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